Antianginal Agents and Vasodilators
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چکیده
“We now know that the coronary blood vessels in the atherosclerotic heart already are dilated and that ordinary doses of dilator drugs do not significantly increase blood supply to the heart; instead, anginal pain is relieved by a reduction of cardiac consumption of oxygen.” Although vasodilators are used in the treatment of angina, a more sophisticated understanding of the hemodynamic response to these agents has broadened their clinical usefulness to other cardiovascular conditions.
منابع مشابه
Metabolic mechanisms associated with antianginal therapy.
Laboratory investigations into preserving viability of the ischemic myocardium or to promote recovery during reperfusion have often focused on the intermediary pathways of energy metabolism. However, in the clinical treatment of angina, the application of metabolic therapies has generally lagged behind or has been incidental to other approaches, such as a vasodilators, calcium antagonists, and ...
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تاریخ انتشار 2012